References

1. Chandra RK, Kern RC, Cutler JL, Welch KC, Russell PT. REMODEL larger cohort with long-term outcomes and meta-analysis of standalone balloon dilation studies. Laryngoscope. 2016 Jan;126(1):44-50.

2. San Nicolo, et al. 2017. Absorbable Implant to Treat Nasal Valve Collapse. Facial Plast Surg, 32:233-240.

3. Data on file. Entellus Medical, Inc. 2018 Investors deck 1808-108 rA slide 7.

4. Rudmick, L, et al. Rhinology-specific priority setting for quality improvement: a modified Delphi study from the Quality Improvement Committee of the American Rhinology Society. Int Forum Allergy & Rhinol. 2017; 7(10): 937-944.

5. American Academy of Otolyaryngology --Head and Nexk Surgery. Chronic sinusitis patients experience improved quality of life after endoscopic sinus surgery. Science Daily. 01.04.2010. https://www.sciencedaily.com/releases/2010/01/100101011826.htm

6. Data on file. Entellus Medical, Inc. 2016 ENT Journal Survey.

7. Kivekas I, Chao WC, Faquin W, et al. Histopathology of balloon dilation Eustachian tuboplasty. Laryngoscope. 2015;125:436-441

8. Data on file. Entellus Medical, Inc. ET Balloon Dilation Clinical Evidence Summary, 1693-130 rA

9. Silvola J, Kivekas I, Poe DS. Balloon Dilation of the Cartilaginous Portion of the Eustachian Tube. Otolaryngol Head Neck Surg. 2014 Jul;151(1):125-30

10. Meyer TA, O'Malley EM, Schlosser RJ, Soler ZM, Cai J, Hoy MJ, Slater PW, Cutler JL, Simpson RJ, Clark MJ, Rizk HG, McRackan TR, D’Esposito CF, Nguyen SA. A randomized controlled trial of balloon dilation as a treatment for persistent Eustachian tube dysfunction with 1-year follow-up. Otol Neurotol. 2018 Aug;39(7):894-902.

11. Value calculated based on 2014 US population estimate from US Census and World Bank data in conjunction with incidence numbers cited in Stewart et al. Epidemiology and burden of nasal congestion. Intl J Gen Med 2010; 2010:3 37-45.

12. San Nicolo M, Stelter K, Sadick H, Bas M, Berghaus A. Absorbable implant to treat nasal valve collapse. Facial Plast Surg. 2017;32:233-240.

13. Sufyan A, Ziebarth M, Crousore N, et al. Nasal batten grafts: are patients satisfied? Arch Facial Plast Surg. 2012;14:14-19.

14. Ramakrishnan JB, Danner CJ, Yee SW. The use of porous polyethylene implants to correct nasal valve collapse. Otolaryngol Head Neck Surg. 2007;136:357-361.

15. Lipan MJ, Most SP. Development of a severity classification system for subjective nasal obstruction. JAMA Facial Plast Surg. 2013;15:358-361.

16. San Nicolo, et al. 2017. Absorbable Implant to Treat Nasal Valve Collapse. Facial Plast Surg, 32:233-240.

17. Becker SS, Dobratz EJ, Stowell N, et al Revision septoplasty: Review of sources of persistent nasal obstruction Am J Rhino. 2008; 22:440-444.

18. Rhee et al. 2014. A systematic review of patient reported nasal obstruction scores: Defining normative and symptomatic ranges in surgical patients. JAMA Facial Plast Surg., 16(3): 219-232.

19. Nasal Obstruction Symptom Evaluation (NOSE) survey is a quality of life survey supported by the AAO Consensus Statement. Otolaryngology–Head and Neck Surgery: 162 STEWART et al February 2004.

20. San Nicoló M, Stelter K, Sadick H, Bas M, Berghaus A. A 2-Year Follow-up Study of an Absorbable Implant to Treat Nasal Valve Collapse. Facial Plast Surg 2018;10.1055/s-0038-1672213.

21. Stolovitzky et al. A prospective study for treatment of nasal valve collapse due to lateral wall insufficiency: Outcomes using a bioabsorbable implant. Laryngoscope. 2018 May 14.

22. Dutton JM. Rhinoplasty (Functional). American Rhinologic Society website. http://care.american-rhinologic.org/rhinoplasty_functional. Accessed August 2018.

23. Fanous N, Brousseau VJ, Karsan N, Fanous A. Predicting the results of rhinoplasty before surgery: Easy noses versus difficult noses. Can J Plast Surg. 2008 Summer;16(2):69-75.

24. Crawford-Brown, Theoretical and Mathematical Foundations of Human Health Risk Analysis; 1997, Page 103.

25. Rhee et al. Nasal Valve Surgery Improves Disease-Specific Quality of Life. Laryngoscope 115: March 2005.

26. Wever, The Nasal Airway: A Critical Review; Facial Plast Surg 2016;32:17–21.

27. Camacho et al, The Effect of Nasal Surgery on Continuous Positive Airway Pressure Device Use and Therapeutic Treatment Pressures: A Systematic Review and Meta-Analysis; SLEEP, Vol. 38, No. 2, 2015. Lin et al, Nasal Aerodynamics. May 14, 2015.

28. Constantian MB, Clardy RB. The Relative Importance of Septal and Nasal Valvular Surgery in Correcting Airway Obstruction in Primary and Secondary Rhinoplasty. Plastic and Reconstructive Surgery. 1996 Jul; 98(1): 47.

29. Ricci, et al. Role of Nasal Valve in the Surgically Corrected Nasal Respiratory Obstruction: Evaluation Through Rhinomanometry. American Journal of Rhinology. September-October 2001, Vol. 15, Nov. 5.

30. Marino MJ, Ling LC, Yao WC, Luong A, Citardi MJ. Eustachian tube dysfunction symptoms in patients treated in a tertiary rhinology clinic. Int Forum Allergy Rhinol. 2017;7:12:1135-1139

31. References and/or published data on file at Entellus Medical, Inc. 3748-001 revB

32. Corrigendum: Optical properties of biological tissues: a review. Steven L Jacques1,2 Published 27 June 2013 • Physics in Medicine & Biology, Volume 58, Number 14 Article link: http://iopscience.iop.org/article/10.1088/0031-9155/58/11/R37/pdf

33. American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS). Intra-Operative Use of Computer Aided Surgery. Accessed May 31, 2016.

34. Antimicrobial, anti-inflammatory, antioxidative, and immune-enhancing properties of chitosan Park BK, Kim MM. Applications of chitin and its derivatives in biological medicine. Int J Mol Sci. 2010;11:5152-5164.

35. Rippy MK, Baron S, Rosenthal M, Senior BA. Evaluation of absorbable PLA nasal implants in an ovine model. Laryngoscope Investig Otolaryngol. 2018 May 25;3(3):156-161. https://onlinelibrary.wiley.com/doi/full/10.1002/lio2.166